"www.healthbusiness.nl"

Transgenomic, Inc. (OTC Bulletin Board: TBIO). In a peer-reviewed paper published in the February 2009 issue of the journal Human Mutation, a team at Weill Cornell Medical College New York describes in detail the key advantages of using Transgenomic’s Surveyor Nuclease technology for mutation scanning of PKD1 and PKD2, two important genes used in the diagnosis and prognosis of autosomal dominant polycystic kidney disease (ADPKD).
Lees meer..

Covaris Incorporated announced the introduction of DNA shearing service using Covaris instruments and technology. Over the past few years, Covaris instruments have become the gold standard for DNA shearing application, as a sample preparation step for next generation sequencing. The Covaris process is validated and compatible with all next-gen sequencing platforms. This process is highly reproducible and gives narrow size distribution.
Lees meer..

IMMUNOLOGY: Girls lacking the protein ITK at risk from fatal viral infection One of the most common viruses to infect humans is EBV. Although most people show no or few signs of infection, some develop glandular fever and boys with mutations in either one of two genes on the X-chromosome (SAP and XIAP) develop a fatal lymphoproliferative disease.
Lees meer..

Ali Shilatifard, Ph.D., Investigator, has joined with a team of colleagues to propose an operational definition of “Epigenetics” – a rapidly growing research field that investigates heritable alterations in gene expression caused by mechanisms other than changes in DNA sequence. Dr.
Lees meer..

A major effort from within the Aspergillus community has resulted in the publication of an exceptional supplement by the Elsevier journal Fungal Genetics and Biology. The supplement provides extensive studies based on the genome analysis of two Aspergillus species: Aspergillus niger and Aspergillus nidulans. The publication was enabled by Eurofungbase, a coordination action programme funded by the European Commission, and was strongly supported by DSM.
Lees meer..

A new study in the April 3rd issue of the journal Cell, a Cell Press publication, helps to explain why people who carry mutations in a gene known as Nurr1 develop a rare, inherited form of Parkinson’s disease, the most prevalent movement disorder in people over the age of 65. They have found evidence that the gene normally acts to suppress an inflammatory response and, in turn, the production of neurotoxins in the brain.
Lees meer..

Light directed at a breast tumor through a needle can provide pathologists with biological specifics of the tumor and help oncologists choose treatment options that would be most effective for that individual patient. Duke University bioengineers have developed a light-based system that can quickly and easily provide important information about oxygen levels within a tumor while it is still in place.
Lees meer..

Researchers have identified a new cancer gene – one that is common to many cancers and affects the most basic regulation of our genes. The new example – a gene on the X chromosome called UTX – is found in 10% of cases of multiple myeloma and 8% of oesophageal cancers. UTX plays a role in overall regulation of the activity of many genes and it is possible that other genes with similar roles will also be found to be involved in different tumour types.
Lees meer..

Researchers have identified a possible genetic cause for increased risk for a more advanced form of colorectal cancer in blacks that leads to shorter survival, according to data published in Clinical Cancer Research, a journal of the American Association for Cancer Research.
Lees meer..

A new national centre to analyse plant, animal and microbial genomes has been announced by the Biotechnology and Biological Sciences Research Council (BBSRC). The Genome Analysis Centre (TGAC) will be based on the Norwich Research Park and will provide genome sequencing to underpin advances to improve food security, to protect UK agriculture from exotic animal disease and exploit weaknesses in microbes to develop new ways to kill superbugs.
Lees meer..