Researchers led by Dr. Soheil Dadras at the Stanford University Medical Center have developed a novel methodology to extract microRNAs from cancer tissues. The related report by Ma et al, “Profiling and discovery of novel miRNAs from formalin-fixed paraffin-embedded melanoma and nodal specimens,” appears in the September 2009 issue of the Journal of Molecular Diagnostics.
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Scientific dogma has long asserted that females are born with their entire lifetime’s supply of eggs, and once they’re gone, they’re gone. New findings by researchers at Fred Hutchinson Cancer Research Center, published online Aug. 27 in Science, suggest that in nematode worms, at least, this does not hold true. Molecular physiologist Marc Van Gilst, Ph.D.
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SATURDAY, Aug. 29 — Ragweed, the bane of many allergy sufferers, will soon be in bloom.
That means several months of itchy, watering eyes, runny nose, sore throat, congestion and problems sleeping for the estimated 36 million Americans with…
September is Gynecologic Cancer Awareness Month, and The Cancer Institute of New Jersey (CINJ) is making experts available to discuss the risks, treatment and prevention options surrounding the various forms of this disease. Gynecologic cancer is the growth and spread of cancer cells in the cervix, ovaries, uterus, fallopian tubes, vagina and vulva. According to the American Cancer Society, 80,600 new cases of gynecologic cancer will be diagnosed nationwide this year with 27,400 deaths.
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Healthy middle-aged women with feelings of hopelessness appear to experience thickening of the neck arteries, which can be a precursor to stroke, according to new research out of the University of Minnesota Medical School.
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Twin monkeys born in a breakthrough experiment conducted in the US could open the way to a new gene therapy that uses a fertility method called spindle transfer to transplant DNA from one egg to another to prevent certain types of inherited diseases passing from mother to offspring. The twin monkeys called “Mito” and “Tracker” are the world’s first animals to be born after using spindle transfer.
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A small molecule earlier found to have both anti-fat and anti-cancer abilities works as a literal turnoff for fat-making genes, according to a new report in the August 28th issue of the journal Chemistry and Biology, a Cell Press journal. The chemical blocks a well known master controller of fat synthesis, a transcription factor known as SREBP. That action in mice that are genetically prone to obesity causes the animals to become leaner.
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Small interfering RNA (siRNA), a type of genetic material, can block potentially harmful activity in cells, such as tumor cell growth. But delivering siRNA successfully to specific cells without adversely affecting other cells has been challenging. University of Iowa researchers have modified siRNA so that it can be injected into the bloodstream and impact targeted cells while producing fewer side effects.
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Since the advent of the Human Genome Project an explosion of data has sent the science world scrambling. There is a growing demand to fine-tune genomic codes, which list the “ingredients for life,” but do not adequately explain how those ingredients function. A Rutgers University-Camden biochemist is addressing this knowledge gap through the creation of a database for quick “background checks” on all known enzyme functions.
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FRIDAY, Aug. 28 — The latest results from the longest-running study yet confirm that surgery is better than artery-opening angioplasty in preventing strokes caused by blockage of the carotid artery, the largest vessel carrying blood to the…