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The Stowers Institute’s Gerton Lab has provided new evidence to clarify the structure of nucleosomes containing Cse4, a centromere-specific histone protein required for proper kinetochore function, which plays a critical role in the process of mitosis. The work, conducted in yeast cells, was published in the most recent issue of Molecular Cell. The centromeric nucleosome acts as a guide for the position of the kinetochore.
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Using an RNA-powered nanomotor, University of Cincinnati (UC) biomedical engineering researchers have successfully developed an artificial pore able to transmit nanoscale material through a membrane. In a study led by UC biomedical engineering professor Peixuan Guo, PhD, members of the UC team inserted the modified core of a nanomotor, a microscopic biological machine, into a lipid membrane.
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University of Toronto researchers have used nanomaterials to develop a microchip sensitive enough to quickly determine the type and severity of a patient’s cancer so that the disease can be detected earlier for more effective treatment. Their groundbreaking work, reported Sept. 27 in Nature Nanotechnology heralds an era when sophisticated molecular diagnostics will become commonplace.
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Doctors can share confidential genetic information about patients in order to protect their relatives, even if patients object, says new GMC guidance on confidentiality, released today, 28th September. For example, when a patient is diagnosed with a disease such as a hereditary form of cancer, doctors could tell their relatives about the potential risk their genetic link could carry.
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Wayne State University officials announced an expansion of a research grant of nearly $2.7 million, bringing the total award to over $6.1 million. This project, funded by the National Institute of Mental Health at the National Institutes of Health, is the first combined imaging and genetics research study on obsessive-compulsive disorder (OCD).
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UCLA scientists have identified two chemicals that convince cells to ignore premature signals to stop producing important proteins. Published in the Sept. 28 edition of The Journal of Experimental Medicine, the findings could lead to new medications for genetic diseases, such as cancer and muscular dystrophy, that are sparked by missing proteins.
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TUESDAY, Sept. 29 — People with nerve pain respond better to a combination treatment using the anticonvulsant gabapentin and antidepressant nortriptyline than to treatment with either drug alone, according to Canadian researchers.
The study…

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TUESDAY, Sept. 29 — If excess weight doesn’t kill you by old age, it could make your life miserable in the form of chronic health problems and impaired mental fitness.
According to a new study, women who are obese in middle age are almost 80…

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TUESDAY, Sept. 29 — A socially isolated, stressful environment can speed up the growth of breast cancer, researchers studying the effects of stress in animal models reported Tuesday.
Social isolation can actually change the expression of genes…

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TUESDAY, Sept. 29 — The economic downturn may not be all bad. In fact, U.S. researchers say recessions may actually be good for health.
University of Michigan researchers looked at death rates during the Great Depression, the worst economic slump…

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