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A panel of leading European diabetes experts led by Professor Oliver Schnell from the Diabetes Research Institute in Munich has published a “Consensus Statement A European perspective” (1) on the benefits of self-monitoring of blood glucose values (SMBG). It recommends performing SMBG for all types of diabetes treatment approaches in order to achieve proper glucose control and values which are close to normal, without increasing the risk of hypoglycaemia.
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Boehringer Ingelheim and GSK, companies with a strong heritage in COPD (chronic obstructive pulmonary disease) and a commitment to improved patient care, have announced their support of The European Federation of Allergy and Airways Diseases Patients` Associations` (EFA) call for urgent improvement in the care of people with COPD.
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Novartis has gained exclusive rights to two oral targeted investigational therapies for patients with a range of life-threatening blood disorders and cancers that currently do not have effective treatment options. Under a licensing agreement with Incyte Corporation, Novartis will have responsibility for the future development of Incyte’s investigational JAK inhibitor outside the US and for future development of an early-stage cmet inhibitor globally.
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(BUSINESS WIRE)–Bristol-Myers Squibb Company (NYSE: BMY) and Otsuka Pharmaceutical Co., Ltd. announced that the U.S. Food and Drug Administration (FDA) has approved the supplemental New Drug Application (sNDA) for ABILIFY® (aripiprazole) for the treatment of irritability associated with autistic disorder in pediatric patients ages 6 to 17 years, including symptoms of aggression towards others, deliberate self-injuriousness, temper tantrums, and quickly changing moods.
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Effient(R) (prasugrel) tablets, a new antiplatelet medicine, was added as a treatment option in two clinical guideline updates: one for patients receiving percutaneous coronary intervention (PCI) and a second one for patients with ST elevation myocardial infarction (STEMI), or severe heart attack.
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A novel approach to classify the gender of six-week-old turkey poults could save millions of male chicks from being killed shortly after birth, according to Dr. Gerald Steiner from the Dresden University of Technology in Germany and his team. Their use of infrared spectroscopy to determine the gender of young birds shows that it is a fast and accurate method with the potential to be used by the breeding industry to identify and select female eggs for breeding.
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Since 1996, crop plants genetically modified to produce bacterial proteins that are toxic to certain insects, yet safe for people, have been planted on more than 200 million hectares worldwide. The popularity of these Bt crops, named after the bacterium Bacillus thuringiensis, comes from their ability to kill some major pests, allowing farmers to save money and lessen environmental impacts by reducing insecticide sprays.
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Whitehead researchers have developed a new type of genetic screen for human cells to pinpoint specific genes and proteins used by pathogens, according to their paper in Science. In most human cell cultures genes are present in two copies: one inherited from the father and one from the mother. Gene inactivation by mutation is therefore inefficient because when one copy is inactivated, the second copy usually remains active and takes over.
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Over the course of a lifetime, the heart pumps some 250 million liters of blood through the body. In order to do this, the muscle fibers of the heart have to be extremely durable. The research group headed by Dr. Wolfgang Rottbauer, vice chair of the Department of Medicine III at Heidelberg University Hospital (Chairman: Prof. Dr. H. A. Katus), has discovered a protein that is responsible for the stability of the smallest muscular unit, the sarcomere.
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Previous studies have indicated that the heparanase (HPA) is correlated with histopathological parameters and poor prognosis of gastric cancers. Although their efficiencies in inhibiting the expression of HPA, the traditional HPA inhibitors may produce nonspecific and undesirable effects. In recent years, genetic approaches targeting HPA have been regarded as a promising alternative.
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