Archive for April, 2011

Shedding Light On The Evolution Of The 2009 Pandemic Influenza A(H1N1) Virus In Japan

Saturday, April 30th, 2011

Analysis of mutations of the 2009 pandemic influenza A(H1N1) virus by researchers at the RIKEN Omics Science Center (OSC) has revealed major genetic differences between the virus in its early phase of infection in Japan and in its peak phase…
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Study Identifies Second Gene Associated With Specific Congenital Heart Defects

Saturday, April 30th, 2011

A gene known to be important in cardiac development has been newly associated with congenital heart malformations that result in obstruction of the left ventricular outflow tract. These are the findings from a study conducted by Nationwide Children’s Hospital and appearing in the journal Birth Defects Research Part A…
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Gene Therapy Shows Promise Against Age-Related Macular Degeneration

Saturday, April 30th, 2011

A gene therapy approach using a protein called CD59, or protectin, shows promise in slowing the signs of age-related macular degeneration (AMD), according to a new in vivo study by researchers at Tufts University School of Medicine…
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New Wrinkle In Genetic Code Revealed By Mutant Mouse

Saturday, April 30th, 2011

Call it a mystery with a stubby tail: an odd-looking mouse discovered through a U.S. government breeding program in the 1940s that had a short, kinky tail and an extra set of ribs in its neck – and nobody knew why. A team of scientists led by researchers at the University of California, San Francisco has now spilled the genetic secrets of this mutant rodent…
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Two Unsuspected Proteins May Hold The Key To Creating Artificial Chromosomes

Saturday, April 30th, 2011

FINDINGS: Whitehead Institute scientists report that two proteins once thought to have only supporting roles, are the true “stars” of the kinetochore assembly process in human cells. RELEVANCE: The kinetochore is vital to proper DNA distribution during cell division…
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Centromere-Independent Kinetochore Assembly – New Insight Into Chromosome Segregation

Saturday, April 30th, 2011

One of the most critical tasks that a dividing cell must accomplish is the successful delivery of a complete set of genetic information to each new daughter cell. Now, a study published by Cell Press in the April 29th issue of the journal Cell, provides fascinating new insight into the complex of proteins that orchestrates the proper segregation of human chromosomes during cell division…
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An Overlooked Detail Of Experimental Design May Invalidate Some Prior Experiments With Nanoparticles

Saturday, April 30th, 2011

Nanoparticles will soon be used as tiny shuttles to deliver genes to cells and drugs to tumors in a more targeted way than was possible in the past. But as the scientists prepare to use the nanoparticles in medicine, concerns have arisen about their potential toxicity…
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New Technique Reveals Functional Gene Networks In A Live Organism

Saturday, April 30th, 2011

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, have developed a new method for discerning the functions of previously uncharacterized genes and placing them in interactive, functional networks that reveal how gene products interact to bring about cellular events…
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Mutations In Single Gene May Have Shaped Human Cerebral Cortex

Saturday, April 30th, 2011

The size and shape of the human cerebral cortex, an evolutionary marvel responsible for everything from Shakespeare’s poetry to the atomic bomb, are largely influenced by mutations in a single gene, according to a team of researchers led by the Yale School of Medicine and three other universities…
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Diabetes in Kids Comes With Hefty Price Tag

Saturday, April 30th, 2011

FRIDAY, April 29 — Medical costs for children and teens with diabetes are six times higher than for other young people in the United States, a new study finds.
Researchers from the U.S. Centers for Disease Control and Prevention examined health…



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